Best practices for data analysis when using UMI adapters to improve variant detection
Best practices for data analysis when using UMI adapters to impro…
Jun 14, 2018
idtdna.com
Advances in next generation sequencing enable the detection of variants at exceptionally low frequencies. The accurate detection of low-frequency variants is challenging due in part to errors that are introduced during sample preparation, target enrichment, and sequencing. After tagging individual DNA library molecules with adapters containing unique molecular identifiers (UMIs), bioinformatic filters can be applied to identify and correct errors introduced during the sequencing workflow. In thi
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Advances in next generation sequencing enable the detection o…
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