Over 240 patients with ATTR-CM treated with tafamidis died over a median follow-up period of 43.2 months. More than a third (39%) of patients with transthyretin-mediated amyloid cardiomyopathy ...

In patients with hemophilia, the knee joints represent approximately 45% of all occurrences of joint bleeding. In patients with hemophilia, the effectiveness of knee replacement surgery is impacted by ...

The lifetime risk of thrombosis in patients with PNH is approximately 50%, and it tends to be found in the abdominal or cerebral veins. Patients who experience thromboses at unusual sites should be ...

Targeted disease-specific therapy should be considered in symptomatic patients with a confirmed diagnosis of post-orthotopic liver transplantation ATTR-CM. Many patients with hereditary ...

The evaluation of suspected cardiac amyloidosis should include screening tests for both AL and ATTR amyloidosis. A strong positive Tc-99 m pyrophosphate (PYP) scan, while generally indicative of ...

The new delivery system could effectively edit the huntingtin (HTT) gene in neurons derived from induced pluripotent stem cells obtained from patients with Huntington disease. A team of researchers ...

Individual patient factors, such as anemia and newly diagnosed ITP, as well as higher-risk procedures, increase the risk of post-procedure bleeding. The risk of bleeding after surgery in patients with ...

BTKi monotherapy significantly prolonged time to next treatment or death compared with BCL-2i+CD20 monoclonal antibody in the second-line setting for CLL/SLL. Patients with chronic lymphocytic ...

Multidisciplinary perisurgical care can best ensure the success of most surgeries for those with hemophilia. An 11-year-old boy presented with pain in his right thigh secondary to a fall 3 days prior.

An entrance to the CHEST 2024 conference in Boston, Massachusetts (Photo by Larry Luxner) The number of treatments for PAH continues to rise, but it still takes an an average of 3 years from symptom ...

Nipocalimab binds FcRn with high specificity, reducing IgG levels while sparing innate and adaptive immune functions. Nipocalimab effectively reduced maternal alloantibodies implicated in fetal and ...

Foramen magnum stenosis was present in 33.3% of children with achondroplasia, highlighting the need for clinically indicated neuroimaging. Children with achondroplasia exhibited sleep architecture and ...