C&EN

Small Molecule-Drug Conjugates: An Emerging Drug Design Strategy for Targeted Therapeutics

Traditional chemotherapeutic agents face challenges due to nonselective cytotoxicity. Targeted therapy, as an essential component of precision medicine, has achieved notable breakthroughs in recent ...
C&EN

Environmentally Benign Synthesis of Anticancer Drug Lenalidomide

Natural Products and Medicinal Chemistry Division, CSIR─Indian Institute of Integrative Medicine, Canal Road, Jammu 180001, India ...
C&EN

Chemotherapeutic Spherical Nucleic Acids

Department of Chemistry, Northwestern University, Evanston, Illinois 60208, United States International Institute for Nanotechnology, Northwestern University, Evanston, Illinois 60208, United States ...
C&EN

Innovative Medicinal Chemistry Strategies for Improving Target Binding Kinetics in Drug Discovery

State Key Laboratory of Esophageal Cancer Prevention and Treatment, Key Laboratory of Advanced Pharmaceutical Technology, Ministry of Education of China, Key Laboratory of Advanced Drug Preparation ...
C&EN

A Metal–Phenolic Network-Coated Coacervate System Mediates Mitochondrial Modulation and Bone Homeostasis Restoration for Postmenopausal Osteoporosis Therapy

Key Laboratory for Ultrafine Materials of Ministry of Education, Frontiers Science Center for Materiobiology and Dynamic Chemistry, Engineering Research Center of Biomedical Materials Ministry of ...
C&EN

Mining Solid-State Electrolytes from Metal–Organic Framework Databases through Large Language Models and Representation Clustering

Tianjin Key Laboratory of Advanced Carbon and Electrochemical Energy Storage, School of Chemical Engineering and Technology, and National Industry-Education Integration Platform of Energy Storage, ...
C&EN

Transition-Metal-Free Site-Selective β- and γ-C–H Borylation of Aliphatic Amines

Department of Chemistry and Biochemistry, The University of Texas at Dallas, Richardson, Texas 75080-3021, United States ...
C&EN

Halogenated Organic Pollutant Degradation Driven by Fe(II) Redox Chemistry

School of Traffic and Environment, Shenzhen Institute of Information Technology, Shenzhen 518172, Guangdong, China ...
C&EN

Metal-Free Photoinduced Halogen-Atom Transfer: A Novel Approach for Tetracoordinate Boron Compound Synthesis and One-Carbon Homologation and Amination of Styrenes

School of Chemistry and Chemical Engineering, Nanchang University, Nanchang, Jiangxi 330031, P. R. China ...
C&EN

Photoetching-Generated Redox Pairs in Confined Layered Structure Boost Single-Electron-Transfer-Mediated Photocatalysis

Hefei National Research Center for Physical Sciences at the Microscale, University of Science and Technology of China, Hefei, Anhui 230026, China ...
C&EN

“De Novo” Construction of Planar-Chiral Ferrocenes via Palladium/Chiral Norbornene Cooperative Catalysis

Engineering Research Center of Organosilicon Compounds and Materials (Ministry of Education), Hubei Key Lab on Organic and Polymeric OptoElectronic Materials, College of Chemistry and Molecular ...
C&EN

Tough and Thermal Insulated Poly(phthalazinone ether sulfone ketone) Aerogel Fibers Fabricated via Ambient Pressure Drying

State Key Laboratory of Fine Chemicals, Liaoning Province Technology Innovation Center of High Performance Resin Materials, Liaoning Key Laboratory of Polymer Science and Engineering, Dalian Key ...