HER2-positive gastric cancer accounts for a substantial proportion of advanced cases and has long been treated with HER2-targeted therapies. While trastuzumab deruxtecan has shown superior activity ...
The Trade-off Between Physiological Authenticity and Experimental Convenience: Navigating the Cellular Foundation of ...
Resistant cells demonstrated global decreases in DNA accessibility with localized opening at resistance-driving loci, ...
Researchers engineered a strain of Listeria monocytogenes that stimulates gamma delta T cells, key innate immune fighters ...
Chronic activation of the stress protein ATF6α promotes aggressive liver tumors by rewiring glucose metabolism and ...
After nearly 40 years of research on how Listeria bacteria manipulate our cells and battle our immune system to cause ...
CD8⁺ T cells are the frontline soldiers of the body against cancer, but their prolonged exposure to tumor antigens often leads to an exhausted state ...
In a significant breakthrough for cancer immunotherapy, collaborative studies published simultaneously in Immunity & ...
2 Tianjin's Clinical Research Center for Cancer, Tianjin, People's Republic of China 3 Tianjin Key Laboratory of Digestive Cancer, Tianjin, People's Republic of China Background Fructose has been ...
Scientists at KAIST have found a way to turn a tumor’s own immune cells into powerful cancer fighters—right inside the body. Tumors are packed with macrophages, immune cells that should attack cancer ...
With this work, her team not only answers questions about EV biology, but also lays the groundwork for next-generation EV-based therapeutics that are both intelligent and adaptable. A new chapter in ...
Cancer remains a major global health challenge, and although immunotherapy has achieved remarkable breakthroughs, its efficacy is often limited by tumor-induced immunosuppression within the tumor ...