More than one million people in the United States are afflicted with Parkinson's disease, a progressive disorder of the brain that affects movement and coordination. The cause is typically unknown, ...

Mutation of DJ-1 is implicated in hereditary Parkinson’s disease. However, the exact molecular mechanism of its pathophysiological role was unknown. Researchers from Japan used molecular simulations ...

Autophagy is a natural, conserved process where cells degrade and recycle their own components, including damaged proteins and organelles. This targeted removal is orchestrated by cargo receptors, ...

Parkinson's disease represents a $6-8 billion market today, projected to exceed $13 billion by the 2030s, driven by rising ...

Verily, Alphabet's health data and AI subsidiary, has been awarded a $14.7 million research grant from the Michael J. Fox Foundation (MJFF) for Parkinson's research to generate a detailed molecular ...

GPR6, a G protein-coupled receptor, is primarily expressed in the medium spiny neurons of the striatum, specifically within the striatopallidal pathway. This pathway is heavily impacted by the loss of ...

Vertero Therapeutics, a clinical-stage biotechnology company breaking barriers in neurodegenerative disease treatment, today announced the appointment of five globally recognized leaders to its ...

An abstract image representing shared mechanisms. Two silhouettes are featured back-to-back with joint cog wheels in bright colors across their heads, representing the shared synaptic mechanism. A ...

Parkinson's disease (PD) is an age-related, progressive neurodegenerative disorder. The hallmark of PD pathogenesis is the ...

The relationship between caffeine and Parkinson’s disease has garnered significant attention in recent years, shifting from initial assumptions of a simple protective effect to more complex insights.