A new Northwestern Medicine study has identified the molecular mechanisms that cause a commonly prescribed antipsychotic drug to produce harmful side effects similar to Parkinson's disease symptoms, ...

Parkinson's and Alzheimer's diseases are the two most common neurodegenerative disorders, affecting millions of people worldwide. Published in the Journal of Neuroscience, new research from the ...

Mutation of DJ-1 is implicated in hereditary Parkinson’s disease. However, the exact molecular mechanism of its pathophysiological role was unknown. Researchers from Japan used molecular simulations ...

Autophagy is a natural, conserved process where cells degrade and recycle their own components, including damaged proteins and organelles. This targeted removal is orchestrated by cargo receptors, ...

More than one million people in the United States are afflicted with Parkinson's disease, a progressive disorder of the brain that affects movement and coordination. The cause is typically unknown, ...

Payami’s study, “Metagenomics of Parkinson’s disease implicates the gut microbiome in multiple disease mechanisms," was recently published in Nature Communications. Payami and her team reported ...

These are really exciting times in the field of Parkinson's disease research. Although the etiology of sporadic disease still remains a mystery, many of the proteins associated with hereditary disease ...

Parkinson’s disease may begin reshaping the body’s chemistry years before the first tremor or stiffness appears. A growing body of peer-reviewed research now ties specific metabolic disturbances, from ...

An abstract image representing shared mechanisms. Two silhouettes are featured back-to-back with joint cog wheels in bright colors across their heads, representing the shared synaptic mechanism. A ...