Huntington’s disease was long thought to be caused by the slow buildup of a toxic protein, but new research has reveale | This week on "The Top Line," we hear from Steven McCarroll, Ph.D., whose ...
HD is a rare, adult-onset, autosomal dominant, progressive neurodegenerative disease. George Huntington (Figure 1) was the first person to provide a comprehensive description of adult-onset HD in ...
Huntington's disease (HD) is a hereditary neurodegenerative disorder caused by a mutation in the gene called huntingtin on chromosome 4. HD is inherited in an autosomal dominant fashion, so that each ...
Hosted on MSN1mon
Surprising way that genetic mutation causes Huntington's disease changes understanding of the disorderThis type of "somatic expansion" occurs in only the specific types of brain cells that later die in Huntington's disease. Only once a cell's DNA expansion reaches a threshold number of CAGs ...
Huntington’s Disease (HD) is a condition that stops parts of the brain working properly over time and is usually fatal. There is no treatment for HD and no cure. “This whole thing around ...
The data were analyzed for linkage to the Huntington's disease gene using the program LIPED with a correction for the late age of onset. Because of the high frequency of the Huntington's disease ...
Huntington’s disease is an inherited neurological disorder causing movement, cognitive, and behavioral issues. Effective management includes medical treatments, therapies, nutritional support ...
ElevateBio is seeking out partnerships for its lead gene therapy after the construct reduced the levels of a toxic protein in ...
A drug originally developed for high blood pressure could find a new use in the treatment of Huntington's disease, thanks to an artificial intelligence-based drug discovery programme at Spain's ...
LETI-101 has demonstrated therapeutically relevant reductions of mutant huntingtin (HTT) protein, exceeding 80%, while preserving essential ...
Brain Changes in Huntington's Disease Decades Before Diagnosis Will Guide Future Prevention Trials Jan. 17, 2025 — Subtle changes in the brain, detectable through advanced imaging, blood and ...
Results that may be inaccessible to you are currently showing.
Hide inaccessible results
Feedback