During pre-mRNA transcription by Pol II, the spliceosome catalyzes two transesterification reactions along the RNA molecule, cleaving it twice and covalently joining adjacent exons, effectively ...

Lipid nanoparticles targeting VEGF mRNA show promise in treating pre-eclampsia, restoring maternal blood pressure and enhancing fetal health in murine models.

Hope for a much-needed treatment for the common pregnancy complication pre-eclampsia has been raised by a successful test of an mRNA therapy in mice ...

They’re turning their backs on a technology thought to have saved millions of lives—with the potential to save many more.