If the Memory Integrity turns on after restart, there must be a system or organization-wide property that overrides the changes. Check this post to know more.

Turn off the toggle for Memory integrity. Reboot your PC. Note: Turning off Memory Integrity reduces system security, especially on Secured-Core PCs.

First, I recommend turning off Memory Integrity and Virtualization Platform features, as Microsoft has noted, even though they are designed to improve security, they can slow down gaming performance.

You can, for example, turn on and off system features to increase the frame rates and experience smoother gameplay, such as Game Mode, GPU scheduling, VRR, Memory Integrity, and virtualization.