The paper develops optimality theory for linear discriminant analysis in the high dimensional setting. A data-driven and tuning-free classification rule, which is based on an adaptive constrained ...

High-dimensional classification is an important and challenging statistical problem. We develop a set of quadratic discriminant rules by simplifying the structure of the covariance matrices instead of ...

The analysis of G-banded chromosomes remains the most important tool available to the clinical cytogeneticist. The analysis is laborious when performed manually, and the utility of automated ...