The classical pathway is initiated by binding of C1q to the pathogen surface, or binding of C1q to antibody/ antigen complexes, forming a link between innate and adaptive immunity.

The classical pathway is triggered by antigen-antibody complexes and includes participation of all complement proteins C1 through C9. The classical pathway is initiated by the binding of C1q to ...

Researchers identified an interleukin 6 dependent alternative pathway as a therapeutic strategy against coronavirus disease 2019.

Celso Bianco, , Zanvil A. Cohn, Regulation of Macrophage Migration by Products of the Complement System, Proceedings of the National Academy of Sciences of the United States of America, Vol. 76, No. 2 ...

“After more than a decade of groundbreaking research targeting the early classical complement pathway, we are excited to have reached an important step in the clinical development of ANX1502 ...

Stuart N. Isaacs, Girish J. Kotwal, Bernard Moss, Immunology, Complement Binding Protein, Vaccinia Virus Complement-Control Protein Prevents Antibody-Dependent Complement-Enhanced Neutralization of ...

“After more than a decade of groundbreaking research targeting the early classical complement pathway, we are excited to have reached an important step in the clinical development of ANX1502 ...

“After more than a decade of groundbreaking research targeting the early classical complement pathway, we are excited to have reached an important step in the clinical development of ANX1502 ...