While adherence to germline testing has been found to be low, one expert explained why tests findings could matter to patients. Undergoing germline testing is of particular importance for patients ...

Genetic testing, including germline and somatic, is vital for prostate cancer prognosis and personalized treatment strategies. PARP inhibitors, targeting BRCA mutations, are a promising therapy for ...

Germline genetic testing can play an essential role in identifying cancer risk, guiding treatment decisions, and informing screening and/or preventive strategies for both patients and patient family ...

Accelerating the Future of Oncology Drug Development: The Role of Consortia in the Delivery of Precision Oncology Early Phase Clinical Trials ASCO Guidelines provide recommendations with comprehensive ...

From 7% to nearly 9% of patients with advanced cancer were found to harbor a germline variant with targeted therapeutic actionability in the first study of its kind. The study involved 11,974 patients ...

More evidence points to the benefits of germline genetic testing for patients with various cancers. Such testing can identify mutations that may warrant a change of treatment and allow trying a ...

Whole Genome Sequencing (WGS) test now available through Foundation Medicine’s FlexOMx Lab™ to support biomarker discovery and drug development across cardiometabolic, immunologic and neurologic ...

Hereditary breast cancer results from inherited mutations, primarily in BRCA1 and BRCA2, increasing lifetime cancer risk. Additional genes like TP53, PTEN, PALB2, CHEK2, and ATM also contribute to ...

"As biopharmaceutical pipelines expand targeted therapies beyond the traditional oncology space and into different areas of medicine, the demand for quality germline data has never been greater,” said ...