One of the primary challenges of genomic data analysis is high dimensionality. The human genome has over three billion base pairs, and many biobanks contain hundreds of thousands of individuals and ...

Dimensionality reduction is often used to visualize complex expression profiling data. Here, we use the Uniform Manifold Approximation and Projection (UMAP) method on published transcript profiles of ...

Scientists are taught early in our training that criticism is a fundamental part of the job. What we are not usually trained to navigate, however, is public backlash, which is exactly what followed ...

When mathematicians Leland McInnes and John Healy walked into their work’s annual “Big Dig” — a sort of classified hackathon for Canada’s version of the National Security Agency — in 2017, they were ...

Sometimes, in the quest for new data, scientists forget that existing datasets can be treasure troves for new discoveries. One such undermined scientific gem is transcriptomic data from the human ...