Transcription and translation are processes a cell uses to make all proteins the body needs to function from information stored in the sequence of bases in DNA. The four bases (C, A, T/U, and G in the ...

Protein translation, also known as protein synthesis, is a fundamental biological process that involves the conversion of the nucleotide sequence in mRNA into a specific sequence of amino acids, ...

The mammalian neocortex comprises an enormous diversity regarding cell types, morphology, and connectivity. In this work, we discover a post-transcriptional mechanism of gene expression regulation, ...

The viral type 2 internal ribosome entry site uses a unique mechanism to hijack the host ribosomal machinery by interacting with initiator tRNA and 40S head.

South Korean researchers have developed an automated, modular cell-free protein synthesis platform that slashes preparation ...

A research team led by Professor Joongoo Lee in the Department of Chemical Engineering at POSTECH (Pohang University of ...

Recent studies have found that some cells of the brain, including neurons, astrocytes, and oligodendrocytes, can transport pieces of the genetic code (RNA) from the nucleus out to their distal ...

The research field of 'cellular IRESes' lay dormant for decades, as there was no uniform standard of reliable methods for the clear characterization of these starting points for the ribosome-mediated ...

In the earliest phase of creating human proteins, the protein complex NAC performs an essential task by starting the first steps toward folding proteins into their correct three-dimensional structures ...

Aging selectively impairs the production of crucial DNA- and RNA-binding proteins, which contributes to hallmarks of aging in the brains of killifish, according to a new study. The findings advance ...

A research team led by Professor Joongoo Lee in the Department of Chemical Engineering at POSTECH (Pohang University of Science and Technology) has ...