The spatial organization of cells is fundamental to multicellular life as it influences development, function and evolution. During development, the precise spatial arrangement of cells ensures proper ...

Spatial transcriptomics technologies can capture gene expression at spatial loci. However, at certain resolutions, the obtained gene expression reflects the sum of either a heterogeneous or ...

Spatial transcriptomics is revolutionizing the study of tissue architecture, cellular states, and tumor-immune interactions in clinical specimens. This presentation introduces the principles and ...

Fei Chen and Chenlei Hu at the Broad Institute of MIT and Harvard have developed a new imaging-free spatial transcriptomics technology that tracks the diffusion of DNA barcodes between beads in an ...