For the immune system to effectively combat pathogens, antibody responses must be precisely controlled. So-called follicular ...

Scientists at St. Jude Children's Research Hospital and Washington University School of Medicine have discovered why the flu vaccine can perform poorly. They found that a specific type of immune cell, ...

For the immune system to effectively combat pathogens, antibody responses must be precisely controlled. So-called follicular ...

Traditionally, in single-variant experiments, cells are engineered to express a single MHC-II allele so that every recovered peptide can be assigned unambiguously, but only a few alleles are covered.

Store-operated calcium entry in CD4 + T helper cells is essential for activation of the transcription factor NFAT, which promotes expression of the T helper 1 cell-lineage-determining transcription ...

After spending years tracing the origin and migration pattern of an unusual type of immune cell in mice, researchers headed by a team at The Ohio State University College of Medicine have shown how ...

For the first time, researchers at the University of British Columbia have demonstrated how to reliably produce an important type of human immune cell-known as helper T cells-from stem cells in a ...