Researchers identify a key pathway leading to neurodegeneration in early stages of ALS, hinting at the potential for short-circuiting the progression of the fatal disease if diagnosed early.
ALS is a progressive disease, meaning it worsens over time. Although there is no cure for ALS, medications and therapies are available to help manage the symptoms, slow the disease course, and prolong ...
This groundbreaking discovery has revealed a systemic metabolic dysfunction that creates a toxic exosome cargo in ALS ...
ALS is characterized by the death of motor neurons, leading to progressive muscle weakness and loss of voluntary movement. Sporadic ALS accounts for approximately 90-95% of cases, while familial ALS ...
People with end stage ALS lose the ability to breathe, have limited mobility as muscles become paralyzed, and may no longer be able to speak. Amyotrophic lateral sclerosis (ALS) affects certain nerve ...
Pictured are nuclei of induced pluripotent stem cell (iPSC)-derived motor neurons stained for contrast. The nucleus on the left has been treated with DMSO (control) and appears mostly blue. The ...
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