Protein acetylation was first discovered on lysine residues of histone tails in 1963 (ref. 1). Since this pivotal discovery, extensive research has revealed the importance of acetylation and other ...

Proteases are pivotal enzymes that catalyse the hydrolysis of peptide bonds, governing processes as diverse as digestion, blood coagulation, immune response and cell signalling. Inhibiting protease ...

A new method developed by researchers at KAIST and Chungnam National University could drastically streamline drug interaction testing—replacing dozens of traditional experiments with just one. The ...

Researchers at the Leibniz Institute on Aging - Fritz Lipmann Institute (FLI) in Jena found that oxidative stress in the aging brain inhibits the activity of deubiquitylases. These enzymes are ...

The results of a preclinical study by lymphoma researchers at Weill Cornell Medicine suggest that an emerging class of anticancer drugs called EZH2 inhibitors may greatly enhance the potency of some ...

Researchers at Karolinska Institutet and Lund University in Sweden have identified a new treatment strategy for neuroblastoma, an aggressive form of childhood cancer. By combining two antioxidant ...

In a new study published in Science Signaling titled, “Restoration of striatal neuroprotective pathways by kinase inhibitor treatment of Parkinson’s linked-LRRK2 mutant mice,” researchers from ...

Please provide your email address to receive an email when new articles are posted on . There was a significant independent link between angiotensin-converting enzyme inhibitor use and all-cause ...

Enzymes are biological catalysts that speed up chemical reactions in living organisms. They are essential for life, as they play a crucial role in various biological processes, such as digestion, ...