A hallmark of Parkinson's disease is the buildup of Lewy bodies—misfolded clumps of the protein known as alpha-synuclein.

HYDRACs are a class of proteomimetic polymers designed to mark harmful proteins, like MYC and KRAS, for destruction rather than merely block their activity.

A University of Massachusetts Amherst scientist has discovered that a mutation in the misfolding protein that causes Parkinson’s disease offers protection against another fatal neurodegenerative ...

Researchers designed polymers that degrade MYC and KRAS by recruiting cellular machinery, slowing tumors and countering drug ...

In humans, hundreds of proteins interact in a complex network dubbed the interactome. Those interactions are further complicated when disease-causing mutations are introduced into genes that code for ...

Proteins often function in pairs or groups, concealing their internal connection points and making it difficult for ...

An estimated 170,000 Australians were diagnosed with cancer in 2025. Many people know the causes of cancer are partly genetic. But how do your genes, which contribute so much of what makes you you, ...

Genes are short sections of DNA that determine an animal’s traits—everything from coat color and claw strength to body shape ...

The search space for protein engineering grows exponentially with complexity. A protein of just 100 amino acids has 20100 ...

A tiny region in a little-known muscle protein may hold the key to a healthy, steady heartbeat, as well as possible clues to ...