Novel generative AI model enables atomic-scale prediction of protein-protein interactions

Proteins are the molecular workhorses of the human body. They perform a vast range of essential functions, from building ...
Nature

CryoAtom improves model building for cryo-EM

Constructing atomic models from cryogenic electron microscopy (cryo-EM) density maps is essential for interpreting molecular mechanisms. Here we present CryoAtom, an approach for de novo model ...
News Medical

Scientists call for explainable AI in protein language models

Protein language models are artificial intelligence tools which help engineer proteins with useful properties, including completely new structures never seen before in nature. The technology has huge ...
Nature

Scaling a foundational protein language model to 100 billion parameters

xTrimoPGLM, a protein language model scaled to 100 billion parameters, showcased scaling behavior to excel in various protein-related tasks. This development advances protein understanding and design, ...
GEN

Protein Dynamics Predicted Rapidly with Generative AI Model, BioEmu

A newly developed generative AI model is helping researchers explore protein dynamics with increased speed. The deep learning system, called BioEmu, predicts the full range of conformations a protein ...
GEN

Biohub Releases Protein Biology World Model to Address Disease

Biohub, the non-profit research organization co-founded by Priscilla Chan, MD, and Mark Zuckerberg, has now unveiled the latest update to the ESM protein language model family, with expanded ...
EurekAlert!

Accuracy test for protein language models shines light into AI 'black box'

Each protein is identified as a point in this scatter plot of data embedded in the language model’s latent space. The red, green and yellow points indicate various subtypes of proteins found in nature ...