Leptin (LEP) is a well known anti-obesity hormone that regulates body weight through its effects on food intake and energy expenditure (Zhang et al. 1994; Halaas et al. 1995; Pelleymounter et al. 1995 ...

Heart failure is a complex clinical syndrome. There is evidence for a genetic contribution to the pathophysiology of heart failure. Considering the fundamental role of neurohormonal factors in the ...

Toll-like receptors (TLRs) are essential components of the immune response to fungal pathogens. We examined the role of TLR polymorphisms in conferring a risk of invasive aspergillosis among ...

Phase I Trial of Yttrium-90—Labeled Anti—Prostate-Specific Membrane Antigen Monoclonal Antibody J591 for Androgen-Independent Prostate Cancer In the future, we will invariably see much more on ...

Polymorphisms in cytokine genes can influence immune responses, inflammation, and tissue injury and may affect the outcome of hematopoietic stem-cell transplantation. Among recipients of hematopoietic ...

“We found that VNTRs can influence gene expression through changes in length or motif dosage,” said Prof. HE. The researchers also examined the distribution patterns of VNTR polymorphisms across ...

Predictors of Specialized Pediatric Palliative Care Involvement and Impact on Patterns of End-of-Life Care in Children With Cancer Three CD40L SNPs (rs3092920, rs3092952, rs3092936) were analyzed for ...

Despite global vaccination efforts, COVID-19 continues to pose significant risks, leading to severe complications and fatalities. These risks are driven by disrupted coagulation, impaired fibrinolysis ...

What are Single Nucleotide Polymorphisms? Single nucleotide polymorphisms (SNPs) are variations in a genome’s base pair in a DNA sequence, and occur in approximately 1 out of 800 base pairs. These ...