These are really exciting times in the field of Parkinson's disease research ... α-synuclein can be internalized by cells suggests a mechanism based on cell–cell transmission.

Lewy body diseases (LBDs) are a class of debilitating neurodegenerative disorders linked to the abnormal aggregation of the ...

In a significant advancement for Parkinson’s Disease (PD) therapy, researchers have developed a targeted nano formulation ...

Apr. 16, 2024 — A new study offers a first look into the complex molecular changes that occur in brain cells with Lewy bodies, which are key pathological hallmarks of Parkinson's disease and ...

Now, a new study from Renmin Hospital of Wuhan University provides strong evidence that kidney failure may also contribute to the development of Parkinson’s disease by triggering the spread of ...

Specific neurons that secrete the neuropeptide oxytocin in the brain are disproportionately disrupted in a mouse model of ...

An enzyme that helps clear damaged mitochondria can act as a molecular switch and potentially prevent neurons from dying.

However, the mechanisms through which caffeine ... influence several pathways that help prevent the onset of Parkinson’s disease. Molecular interactions are thought to be key in this prevention ...

Scientists from the Institute of Nano Science and Technology (INST) Mohali, an autonomous institute of the Department of ...

Parkinson's disease is a common brain disorder that ... inducer of mitophagy to mitigate Parkinson's. To decode the molecular mechanism behind melatonin-mediated oxidative stress regulation ...

New research uncovers how declining protein clearance mechanisms with age lead to Alzheimer’s, Parkinson’s, and other ...

Dyskinesia hampers the quality of life for most Parkinson's disease patients following several ... but instead unmasks or exacerbates sensitization mechanisms (the first drug dose would highlight ...