Figure 1. Optical pooled screens and PerturbView. a) Optical pooled screens (OPS) use targeted in situ sequencing of perturbations to link phenotypes and genotypes from a pooled library, making it ...

Genetic screens are critical for the systematic identification of genes underlying cellular phenotypes. While pooling gene perturbations can greatly increase screening throughput, this approach was ...

Visualizing cells after editing specific genes can help scientists learn new details about the function of those genes. But using microscopy to do this at scale can be challenging, particularly when ...

Pooled genetic screening is a powerful approach to study how different genotypes contribute to cellular phenotypes. Although traditional CRISPR screening can assay phenotypes, it requires cell ...

COVID-19 outbreaks have caused enormous economic losses and have posed health risks, particularly among disadvantaged populations. Testing plays a critical role in containing these outbreaks and ...

Semarion Ltd, a University of Cambridge spin-out company from the Cavendish Laboratory combining materials engineering and cell biology to tackle unmet drug screening needs, today introduced its ...