Several studies showed that supplementation of oviductal extracellular vesicles (EVs) enhanced the development and quality of the early embryos cultured in vitro. However, our previous study found ...

Sexual reproduction begins with sperm–oocyte fusion to form a zygote, where chromatin undergoes dramatic reorganization to establish totipotency. Although nucleosomes- the basic units of eukaryotic ...

Changes in cellular metabolites have been shown to regulate embryonic stem cell development at the earliest stages of life. Metabolites are simple compounds generated during life-sustaining chemical ...