Thirty years after its discovery, scientists are eyeing leptin with renewed interest, for everything from weight loss drug ...

Plasma leptin levels were linked with Alzheimer's disease PET pathology in cognitively unimpaired older adults in Korea. Lower baseline leptin was associated with a greater increase in tau over 2 ...

Metabolic dysfunction-associated fatty liver disease (MAFLD) has emerged as a predominant chronic liver condition globally, intricately linked with obesity, type 2 diabetes (T2DM), and metabolic ...

Polyphenol-rich berries may improve insulin sensitivity, regulate leptin, and modestly boost memory while influencing amyloid and tau pathways in obesity-related decline.

For more than a hundred years, insulin has been the key to controlling type 1 diabetes. It has saved lives by preventing diabetic ketoacidosis (DKA), a life-threatening condition that happens when the ...

Axons from AgRP neurons, in red, innervate oxytocin neurons, in green, in the PVH. Neuronal activity of AgRP neurons is required for normal targeting of their axons to oxytocin neurons, as well as for ...

Researchers from the lab of Richard Simerly have uncovered the first example of activity-dependent development of hypothalamic neural circuitry. The work also suggests a novel role for the hunger ...