Universal solid tumor therapy with CD5-deleted, DSG2-directed CAR-T cells. This is an ASCO Meeting Abstract from the 2025 ASCO Annual Meeting I. This abstract does not include a full text component.

Cytotoxic T lymphocytes are the body's specialized "killer" cells, precisely eliminating infected or cancerous cells. Their action relies on a specialized exchange zone called the "immune synapse," ...

The body’s “killer” T cells don’t just attack—they strike with astonishing precision, forming a tiny, highly organized contact zone that lets them destroy dangerous cells without harming their ...

Cytotoxic T lymphocytes are the body's specialized "killer" cells, precisely eliminating infected or cancerous cells. Their action relies on a specialized exchange zone called the "immune synapse," ...

Why do immune cells that are supposed to eliminate viruses suddenly turn against our own body? There are instances where killer T cells—which are meant to precisely remove virus-infected ...

Researchers have found a reliable way to grow helper T cells from stem cells, solving a major challenge in immune-based cancer therapy. Helper T cells act as the immune system’s coordinators, helping ...

Scientists have made great progress in harnessing the body's own immune cells to treat so-called liquid tumors, cancers of the blood and lymphatic system. Yet these powerful cell therapies have been ...

Immunometabolism, the intersection of cellular metabolism and immune function, has revolutionized our understanding of T cell biology. Changes in cellular metabolism help guide the development of ...

As the trained killers of the immune system, cytotoxic T cells silently save our lives every day—vanquishing viruses before they can run amok, and putting nascent cancer cells out of business before ...

Researchers at UC San Francisco have uncovered a new clue to how Epstein-Barr virus (EBV) could contribute to multiple sclerosis (MS), a chronic autoimmune disease that affects nearly one million ...