Labroots

Over One Million Autonomous Exons Lurk in the Human Genome

In the genome, genes that code for protein are often divided into sections called exons, which are separated by spacers called introns. When a region of DNA is transcribed into messenger RNA (mRNA) or ...
Nature

Optimized convolutional neural network using African vulture optimization algorithm for the detection of exons

The detection of exons is an important area of research in genomic sequence analysis. Many signal-processing methods have been established successfully for detecting the exons based on their ...
Nature

Refining clinically relevant parameters for mis-splicing risk in shortened introns with donor-to-branchpoint space constraint

Precursor mRNA splicing to remove introns and join exons, producing mature mRNA, is a key regulatory step for gene expression. Canonical pre-mRNA splicing of introns is catalysed by a large complex of ...
GEN

ExpressionEdits Partners with Boehringer to Enhance Gene Therapies with AI-Based Intron Design

While working on a COVID-19-related project during the lockdown, Kärt Tomberg, PhD, found herself thinking about introns. She was part of a team working on the spike protein used in vaccines. Her task ...