The results, published May 5 in Nature Genetics, offer a new way to understand the molecular roots of cancer — an especially ...

Researchers have created the first complete map showing how hundreds of mutations in a key cancer gene affect tumor growth. By testing every possible mutation in a critical hotspot, they found that ...

A gene known as CTNNB1 encodes for a crucial protein called β-catenin, which has an important role in controlling tissue repair and cell growth. If this gene and its protein are dysfunctional, it can ...

Scientists at Fox Chase Cancer Center have identified a mutation in a common oncogene - a gene that can cause cancer - that may play an important role in colon cancer. Researchers also showed how this ...

A single-cell platform reveals that many genetic mutations converge on shared cellular programs, pointing to simpler, more ...

New clinical trial data show KRAS-blocking drugs may significantly improve survival for the disease. “I think this is truly ...

Dysfunction resulting from mitochondrial DNA mutations has been implicated in multiple human pathologies, including ...

Researchers working on an incurable blood cancer can now use a new lab model that could make testing potential new treatments and diagnostics easier and quicker, new research has found. Working with ...

Two new studies from Karolinska Institutet in Sweden have investigated how mutations that occur in muscles and blood vessels over time can affect aging. The studies, which are published in Nature ...