The transcription factor XBP1 has been linked to the development of highly secretory tissues such as plasma cells and Paneth cells, yet its function in granulocyte maturation has remained unknown.

Eosinophils have been traditionally perceived as terminally differentiated cytotoxic effector cells. Recent studies have provided a more sophisticated understanding of eosinophil effector functions ...

Researchers in Sweden have provided a comprehensive characterization of circulating granulocytes in people infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that ...

Mucosal surfaces serve as critical battlegrounds where the immune system must balance tolerance to commensal organisms with rapid defense against pathogens.

Eosinophils are specialized pro-inflammatory white blood cells. They have a bilobed nucleus and are granulocytes, which means they contain granules within their cytoplasm. These granules contain ...

High eosinophil levels may indicate an immune reaction to infection, cancer, or allergens. Low eosinophil levels may result from alcohol intoxication or indicate an underlying hormone disorder.

Background and Objective: Endothelin-1 (ET-1) is produced by vascular endothelial cells and epithelial cells, T-lymphocytes and phagocytes. Increased ET-1 levels have been demonstrated in the ...

Background. Eosinophils are a prominent cell type in the host response to helminths, and some evidence suggests that neutrophils might also play a role. However, little is known about the activation ...

Granulocytes should be transfused ABO- and Rhesus-compatible as there is always a significant RBC contamination. If the recipient is cytomegalo virus-negative concentrates from cytomegalo ...