A glycosyltransferase (GT) inhibitor with a novel mechanism of action could aid glycobiology research and drug discovery, according to a report in Nature Chemical Biology (DOI: 10.1038/nchembio.343).

Recent evidence suggests that natural products are much more than simply agents of “microbial warfare” and actually play critical roles in bacterial pathogenesis and communication. In particular, ...

An effective treatment could be found for one of the most aggressive pediatric cancers, alveolar rhabdomyosarcoma (aRMS). These kinds of tumors, which develop mainly in skeletal muscle, are ...

Given the common use of ACE inhibitors and ARBs worldwide, guidance on the use of these drugs in patients with Covid-19 is urgently needed. Here, we highlight that the data in humans are too limited ...

A protein that has long frustrated diabetes researchers is suddenly at the center of a very different fight. By targeting an enzyme called protein tyrosine phosphatase 1B, or PTP1B, scientists are ...

Urbana –University of Illinois scientist Tim Garrow, in collaboration with Jiri Jiracek of the Czech Academy of Sciences, has applied for a provisional patent on a class of chemicals that has future ...

Renin–angiotensin system (RAS) inhibitors — including angiotensin-converting–enzyme (ACE) inhibitors and angiotensin-receptor blockers (ARBs) — slow the progression of mild or moderate chronic kidney ...

Cardiovascular illnesses, such as high blood pressure and heart problems, are often treated with angiotensin-converting enzyme (ACE) inhibitors. The ACE inhibitors lower blood pressure by relaxing ...

The COVID-19 pandemic has still not been countered by effective drugs or antivirals, which is the reason for the continued restrictions on mobility and social interactions in most countries the world ...

Please provide your email address to receive an email when new articles are posted on . There was a significant independent link between angiotensin-converting enzyme inhibitor use and all-cause ...