Every time a cell divides, it must copy its entire genome so that each daughter cell inherits a complete set of DNA. During that process, enzymes known as polymerases race along the DNA to copy its ...

For almost 60 years, scientists have tried to understand why DNA doesn't replicate wildly and uncontrollably every time a ...

If severe DNA damage is not repaired, the consequences for the health of cells and tissues are dramatic. A study led by ...

Unrepaired DNA-protein crosslinks (DPCs) – highly toxic tangles of protein and DNA – cause a process that leads to premature ...

Although DNA is tightly packed and protected within the cell nucleus, it is constantly threatened by damage from normal ...

For almost 60 years, scientists have tried to understand why DNA doesn't replicate wildly and uncontrollably every time a cell divides – which they need to do constantly. Without this process, we ...

A new mouse study found that unrepaired DNA-protein crosslinks activate inflammatory signaling pathways that trigger early aging disorders.

Scientists at the University of Leicester have captured the first detailed “molecular movie” showing DNA being unzipped at the atomic level – revealing how cells begin the crucial process of copying ...

The human genome has to be carefully organized so it will fit inside of the nuclei of cells, while also remaining accessible ...

In a way, sequencing DNA is very simple: There's a molecule, you look at it, and you write down what you find. You'd think it would be easy—and, for any one letter in the sequence, it is. The problem ...

Scientists have captured the first detailed 'molecular movie' showing DNA being unzipped at the atomic level -- revealing how cells begin the crucial process of copying their genetic material.