The complement system is an essential part of the innate immunity that is involved in the elimination of pathogens as well as participating in the body’s immune surveillance against cancer. However, ...

Historically, three pathways have been shown to activate the complement cascade. Recently, Lan et al. and Donado et al. independently reported that granzyme K expressed by CD8 + T cells is capable of ...

Omaveloxolone (approved for Friedreich's ataxia) may help protect cells from stress and correct underlying dysfunction in SMA ...

Lysins are specific antibodies that cause the dissolution of bacteria, plant, and animal cells. Under the influence of ...

Please provide your email address to receive an email when new articles are posted on . A protein known as granzyme K was recently shown to be a driver of inflammation by activating the complement ...

Discoveries may help to explain why some bacteria are hard to eliminate, and also point to potential future approaches to improving antibiotic effectiveness.

Our bodies response to invading pathogens through different mechanisms of the immune system. Innate immunity first detects disease and relays a defense signal to activate the second wave of immune ...