The anti-tumor immune response involves a series of complex steps mediated by various immune cells and signaling molecules. Cytotoxic T cells (CTLs), also known as “killer” T cells, play a central ...
Carfilzomib prevented BCMA degradation, increased target density, and improved CAR T susceptibility by ~26%–28% in vitro, while enhancing xenograft antitumor activity without worsening T-cell ...
In a significant breakthrough for cancer immunotherapy, collaborative studies published simultaneously in Immunity & Inflammation and Nature have demonstrated a critical molecular mechanism that ...