Typical workflow of computational cell lineage tracing. The workflow includes cell labeling, data acquisition, trajectory inference, and lineage reconstruction and visualization. Over the past two ...

August Weismann's germ plasm theory of the late 19 th century posited that only germ cells, e.g., sperm and egg cells in animals or pollen and ovule cells in plants, transmit genetic information to ...

Lineage tracing is a powerful tool to study development, tissue homeostasis, aging, and disease progression. Over the past decades, lineage tracing ...

Over the past decades, lineage tracing has been fundamental to unraveling how diverse cell types arise during development and how tumors evolve ...