A team led by Professor Kazuhiro Maeshima of the National Institute of Genetics (ROIS) and SOKENDAI in Japan has developed a method to visualize different types of chromatin and reveal their distinct ...

A new technology developed at MIT enables scientists to label proteins across millions of individual cells in fully intact 3D tissues with unprecedented speed, uniformity, and versatility. Using the ...

Cell-to-cell communication through nanosized particles, working as messengers and carriers, can now be analyzed in a whole new way, thanks to a new method involving CRISPR gene-editing technology. The ...

Dynamic protein distribution within and across the plasma membrane is pivotal in regulating cell communication. However, rapid, high-density labeling methods for multiplexed live imaging across ...

Biotium, a leading innovator in fluorescent dyes and life science reagents, announces the launch of GlycoLiner™ Cell Surface Glycoprotein Labeling Kits for rapid, selective, and covalent labeling of ...

Subcellular lipid composition and transport significantly influence the physiological and pathological functions of both cells and organelles. However, lipid transport and turnover between organelles ...

Targeting cells for ablation, gene therapy or drug delivery is an ongoing challenge in development of therapeutics. With the goal of efficiently labeling cell surfaces based on target recognition, we ...

Tissue processing advance can label proteins at the level of individual cells across whole, intact rodent brains and other large samples just as fast and uniformly as in dissociated single cells. A ...

Movie 1: Movement of single nucleosomes in living human cells. The movie shows nucleosome fluctuations in euchromatin (left), where gene expression is active, and in heterochromatin (right), where ...

Profiling the proteins that cells are making is a staple of studies in biology, neuroscience and related fields because the proteins a cell is expressing at a given moment can reflect the functions ...

A mouse brain hemisphere stained with various cell type makers: neurons overall (cyan), and cells specifically involved with neurotransmitters dopamine (yellow) and acetylcholine (magenta). A new ...