Researchers have identified a tissue-repair program that colon cancer cells may exploit to spread, with obesity potentially intensifying the effect through changes in lipid metabolism. Credit: ...

Colorectal cancer remains one of the most common and lethal malignancies worldwide, and while immune checkpoint inhibitors ...

S-palmitoylation, a reversible lipid-based post-translational modification, is notably elevated in colorectal cancer (CRC) due to common lipid metabolism disorders. It has been reported to play ...

Changes in metabolic activity in tumor cells is one of the hallmarks of cancer. Cancer cells exhibit the Warburg effect with high glucose consumption for their energy needs. This ...

Immune cells can reach head and neck tumors, but once there, many stop functioning. This helps explain why immunotherapy with ...

The ketogenic diet, long known as a high-fat, very-low-carbohydrate regimen used to treat epilepsy, is now being reframed as ...

Clear cell renal cell carcinoma (ccRCC), the most common subtype of kidney cancer, is increasingly understood as a malignancy ...

Lipid metabolism has emerged as a central player in the progression and therapy resistance of breast cancer, particularly the aggressive subtype known as triple-negative breast cancer (TNBC). This ...

Clear cell renal cell carcinoma (ccRCC), the most common subtype of kidney cancer, is increasingly understood as a malignancy ...

High-risk MDS stem cells appear to have an unexpected “energy addiction,” relying far more heavily than healthy blood-forming cells on a molecule called NAD. Disrupting this energy pathway selectively ...

Nicotinamide riboside, or NR, is a form of vitamin B3 that is widely sold as a dietary supplement. It has attracted attention ...