Chemotherapy faces a fundamental problem: The same drugs powerful enough to kill cancer cells can also damage healthy tissue. UC Irvine researchers are trying to change that equation by putting a ...

Signal transduction in Saccharomyces cerevisiae orchestrates cellular responses to environmental cues via conserved modules. The pheromone response pathway uses G-protein-coupled receptors to activate ...

Microbial survival and adaptation often rely on the precise detection of small diatomic gases such as oxygen, carbon monoxide and nitric oxide. Central to this capacity are heme prosthetic groups, in ...