Scientists show that neutralizing liver-derived ApoE protein reverses age-related delays in bone fracture healing ...

Two rare mutations in the APOE gene ― APOE ε4 (R251G) and APOE ε3 (V236E) ― dramatically reduce the risk of developing Alzheimer's disease (AD), results of a large genetic association study show. APOE ...

Is the IDOL enzyme the key to stopping Alzheimer's? New research shows that blocking this single target can dissolve brain plaques and boost cognitive resilience.

A flurry of recent studies implicating microglia as key players in neurodegenerative diseases, particularly Alzheimer’s, has cued many labs to try to figure out how these cells function in health, and ...

ApoE research is not just about its three main alleles. You may have heard the words Christchurch and Jacksonville in connection with ApoE, but did you know that well over 100 variants have been ...

Despite its strong influence, APOE is not the sole cause of Alzheimer’s or other dementias. Even among people with the highest genetic risk, those who carry two ε4 variants, lifetime risk of Alzheimer ...

Using the largest sample of super-agers to date, scientists have found convincing evidence that supports what many of us have suspected: Longevity isn’t just about healthy lifestyle choices, but also ...

Please provide your email address to receive an email when new articles are posted on . The APOE e4 allele correlated with earlier clinical and biomarker-related changes of Alzheimer’s disease among ...