Ataxia-telangiectasia (A-T) is an autosomal recessive chromosome breakage disorder caused by mutations in the ATM gene. Typically, it presents in early childhood with progressive cerebellar ...

The possible role of the ATM gene in cancer predisposition in the general population made it a target for screening in different malignancies. Loss of heterozygosity at the ATM gene and ATM protein ...

See related articles at www.cmaj.ca/lookup/doi/10.1503/cmaj.191660 and www.cmaj.ca/lookup/doi/10.1503/cmaj.191194 An otherwise healthy 4-year-old boy was brought to ...

Difficulty balancing or an inability to do so can be caused by any number of factors. Head injuries, migraines, alcohol use, ear infections and medications can all affect your musculoskeletal system ...

Mixed Response in Interim Positron Emission Tomography/Computed Tomography Leads to Detection of a Gastrointestinal Stromal Tumor in a Patient With Mediastinal Diffuse Large B-Cell Lymphoma ...

If you have impaired muscle coordination or control, you might have a type of ataxia. This condition is rare, but it can make it difficult to maintain balance, speak, or move. “Ataxia” is the medical ...

A 75 year-old woman developed the acute onset of ataxia, diplopia and confusion. Multiple Brainstem and Cerebellar Infarctions: Diffusion-weighted MRIs. Note the bright signal indicating acute ...

Friedreich’s ataxia is a rare genetic disease that causes difficulty walking, a loss of sensation in the arms and legs, and impaired speech. It’s also known as spinocerebellar degeneration. “Ataxia” ...

Vitamin B12’s contribution to the body is invaluable. Among other things, it helps make red blood cells and keeps your nervous system operating efficiently. Having consistently low B12 levels ...