As for the top, the new No. 1 team is the Detroit Lions. After losing at Green Bay to open the season, the Lions have ripped off four straight as Jared Goff has played at an MVP level. They have some defensive flaws still, but which team doesn't have issues? Oh, and they can score.

Ralph Vacchiano is an NFL Reporter for FOX Sports. He spent six years covering the Giants and Jets for SNY TV in New York, and before that, 16 years covering the Giants and the NFL for the New York Daily News. Follow him on Twitter at @RalphVacchiano.

We stacked every NFL team ahead of Week 6. Which teams rose into or fell out of the top 10? Plus, we have fantasy surprises on each roster.

Week 6 will conclude with another Monday Night Football doubleheader. The Buffalo Bills (4-1) will visit the Atlanta Falcons (2-2) and the Chicago Bears (2-2) will visit the Washington Commanders (3-2).

Week 5 was one of the more unpredictable ones we've seen in the early 2025 NFL season. Fortunately for fantasy managers, it didn't bring another avalanche of significant injuries.

As the Eagles head into Week 6 coming off their first loss of the season, they have moved down in most power rankings. Here’s where they stand.

13. Seahawks (No. 10; 3-2): If they play the Bucs in the playoffs, here’s hoping the league lets both teams wear the old uniforms again. 14. Patriots (No. 23; 3-2): Coupled with North Carolina getting blown out (again), it was the franchise’s best weekend since winning Super Bowl LIII.

Week 6 is set to kick off with a Thursday night matchup between the Philadelphia Eagles and New York Giants. If the upcoming slate is anything like the NFL's most recent one, fantasy managers are in for a roller-coaster ride.

NFL Fantasy Analyst Michael F. Florio gives his favorite fantasy football waiver wire targets for Week 6.