The end of Brandon Aiyuk's tenure with the San Francisco 49ers took another step toward becoming official. San Francisco announced on Saturday that Aiyuk has been placed on the reserve/left squad list, officially ending his ability to play during the 2025 season.

George Kittle cast doubt on Brandon Aiyuk’s return as Dianna Russini reports the 49ers’ optimism has “run out” and a decision is coming. The post 49ers Hear Grim Brandon Aiyuk Update After George Kittle’s Quote appeared first on Heavy Sports.

Per ESPN’s Dan Graziano and Jeremy Fowler, the Commanders are viewed in league circles as a strong potential landing spot for 49ers WR Brandon Aiyuk this offseason. Aiyuk played with Commanders QB Jayden Daniels at Arizona State and the two are close.

Brandon Aiyuk’s ties to Jayden Daniels are fueling Commanders rumors as the team weighs its offseason plans around their injured QB.